Non-covalent immobilized sultone based protic ionic liquids on nano silica sulfuric acid as novel heterogeneous catalysts for the efficient synthesis of tetrazolopyrimidines

In this research work, a novel strategy for the heterogenization of sultone based acidic ionic liquids via their non-covalent immobilization on nano silica sulfuric acid is reported and catalytic ability prepared heterogeneous catalysts synthesis tetrazolopyrimidines derivatives investigated. The physicochemical properties were studied using thermal spectroscopic techniques such as 1H 13C NMR, FTIR, SEM, TEM, TGA, EDX BET. following, three-component reaction aromatic aldehydes, active methylene compounds 5-aminotetrazole to achieve tetrazolopyrimidine products in presence introduced supported new organic–inorganic nanohybrid was performed. obtained results showed that protic have better activity than non-supported forms. Moreover, recoverability, reusability stability also significantly improved by acid.